I'm no longer linking to the Singularity institute blog, as I do no longer wish to be associated with this organization in any way. Dresden Codak gets the boot for displaying Megatokyo Syndrome (glacial pacing, asking for donations for broken computers, etc.) and Pink Tentacle seems, sadly, to be defunct since April (I dearly hope this guy is OK).
Replacing them are Gene Expression, a blog on "human evolution, genetics, genomics and their interstices"; something like a 21st century Rassenlehre without any of the associated wickedness; Hark! A Vagrant, a webcomic, by the wonderful Kate Beaton, on topics like Sherlock Holmes, Canadians, Tesla, Chopin and Liszt, book covers, and much more; and Monsieur LaMoe (moderately NSFW), who lends a unique voice to the world's hikikomori, and whose status as a real person vs. a consortium of writers is still under debate. (I'm leaning somewhat towards "real person".)